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How long does it take prednisone to get out of your system?

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It takes approximately 16.5 to 22 hours for Prednisone to be out of your system. The elimination half life of prednisone is around 3 to 4 hours. This is the time it takes for your body to reduce the plasma levels by half. It usually takes around 5.5 x half-life for a drug to be completely eliminated from your system.
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